Al-Hashimi Lab

Lab Members

Principal Investigator

  • Hashim M. Al-Hashimi, PhD

    • VP&S Associate Dean of Biomedical Graduate Education
    • Roy and Diana Vagelos Professor of Biochemistry and Molecular Biophysics
    • 2024-present Associate Dean of Biomedical Graduate Education | Vagelos College of Physicians and Surgeons | Columbia University
    • 2023-present Co-Founder and Platform Architect | Base4 Inc., Durham, NC
    • 2022-present Roy and Diana Vagelos Professor | Biochemistry & Molecular Biophysics | Columbia University
    • 2015-2022 James B. Duke Professor | Biochemistry & Chemistry | Duke University
    • 2014-2015 Professor | Biochemistry & Chemistry | Duke University
    • 2012-2013 J. Lawrence Oncley Professor | Chemistry | University of Michigan
    • 2009-2023 Co-Founder and Platform Architect | Nymirum Inc., Durham, NC
    • 2009-2013 Professor | Biophysics | University of Michigan
    • 2009-2012 Robert L. Kuczkowski Professor | Chemistry | University of Michigan
    • 2008-2009 Associate Professor | Chemistry & Biophysics | University of Michigan
    • 2002-2008 Assistant Professor | Chemistry & Biophysics | University of Michigan
    • 2000-2002 Postdoctoral Researcher (Dr. Dinshaw Patel) | Memorial Sloan-Kettering Cancer Center, New York, NY
    • 2000 Ph.D. Biophysical Chemistry (Dr. James Prestegard) | Yale University
    • 1995 B.S. Chemistry | Imperial College London, London, UK
    • 1992 I.B. United World College of Atlantic, Wales, UK

Postdoctoral Researchers

  • Dr. Or Szekely

    • 2020-present Postdoctoral Researcher | Duke University
    • 2018-2020 Postdoctoral Researcher (Dr. Rina Rosenzweig) | Weizmann Institute of Science, Rehovot, Israel
    • 2018 Ph.D. Chemical and Biological Physics (Dr. Lucio Frydman) | Weizmann Institute of Science, Rehovot, Israel
    • 2010 M.S. Physical Chemistry | Hebrew University of Jerusalem, Jerusalem, Israel
    • 2008 B.S. Physical Chemistry | Hebrew University of Jerusalem, Jerusalem, Israel

  • Dr. Supriya Pratihar

    • 2022-present Postdoctoral Researcher | Columbia University
    • 2021-2022 Postdoctoral Researcher (Dr. Christian Griesinger) | Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany
    • 2021 Ph.D. Chemistry (Dr. Christian Griesinger) | Max Planck Institute for Biophysical Chemistry, Göttingen, Germany
    • 2013 M.S. Chemistry (Dr. Ramakrishna V. Hosur) | Tata Institute of Fundamental Research, Mumbai, India
    • 2009 B.S. Chemistry | Calcutta University, West Bengal, India

  • Dr. Serafima Guseva

    • 2022-present Postdoctoral Researcher | Columbia University
    • 2021 Ph.D. Structural Biology (Dr. Rob W. H. Ruigrok & Dr. Martin Blackledge) | Université Grenoble Alpes, Saint-Martin-d'Hères, France
    • 2017 M.S. Integrated Structural Biology (Dr. Winfried Weissenhorn) | Université Grenoble Alpes, Saint-Martin-d'Hères, France
    • 2016 M.S. Biophysics (Dr. Valentin Gordeliy) | Moscow State University, Moscow, Russia
    • 2015 B.S. Biology | Moscow State University, Moscow, Russia

Graduate Students

  • Ainan Geng

    • 2022-present Non-degree Graduate Student | Biochemistry and Molecular Biophysics | Columbia University
    • 2019-present Graduate Student | Biochemistry | Duke University
    • 2019 B.S. Intensive Instruction in Sciences and Arts | Nanjing University, Nanjing, China

  • Rohit Roy

    • 2022-present Non-degree Graduate Student | Biochemistry and Molecular Biophysics | Columbia University
    • 2019-present Graduate Student | Computational Biology and Bioinformatics | Duke University
    • 2019 B.S. Bioengineering | Indian Institute of Technology, Kharagpur, India

  • Yeongjoon Lee

    • 2022-present Graduate Student | Biochemistry and Molecular Biophysics | Columbia University
    • 2021-2022 Graduate Student | Biochemistry | Duke University
    • 2020-2021 Researcher (Dr. Woonghee Lee) | University of Colorado Denver
    • 2019 M.S. Bioscience and Biotechnology (Dr. Yangmee Kim) | Konkuk University, Seoul, Korea
    • 2017 B.S. Systems Biotechnology | Konkuk University, Seoul, Korea

  • Aiyana Monae

    • 2022-present Graduate Student | Cellular and Molecular Physiology and Biophysics | Columbia University
    • 2021 B.S. Biochemistry and Anthropology | State University of New York College at Oneonta

  • Alicia N. Chime

    • 2022-present Graduate Student | Pathobiology and Mechanisms of Disease | Columbia University
    • 2020-2022 Researcher (Dr. Sujatha Kannan) | Johns Hopkins University School of Medicine
    • 2020 B.S. Neural Science | New York University
    • 2018-2020 Undergraduate Researcher (Dr. Eric Klann) | New York University

  • Minh-Chau (Rachel) Nguyen

    • 2023-present Graduate Student | Biochemistry and Molecular Biophysics | Columbia University
    • 2023 B.A. Biochemistry and Molecular Biophysics | Wesleyan University

  • Joshua A. Cooksey

    • 2023-present Graduate Student | Biochemistry and Molecular Biophysics | Columbia University
    • 2023 B.S. Biochemistry | University of Maryland, College Park

Master's and Undergraduate Students

  • Linshu (Lance) Li

    • 2025-present Post-master’s Researcher | Columbia University
    • 2025 M.S. Biological Science | Columbia University
    • 2023 B.S. Biochemistry | University of Washington, Seattle

  • Subin B. Shetty

    •  2023-present Undergraduate Researcher | Columbia University

  • Amruta Turlapati

    • 2024-present Undergraduate Researcher | Columbia University

  • Yasuko Yoshida

    • 2024-present Undergraduate Researcher | Columbia University

  • Harini Thiruvengadam

    • 2024-present Undergraduate Researcher | Columbia University

Former Post-docs

  • Dr. Hala Abou Assi

    • Postdoctoral Fellow 2018-2022
    • Presently Research Scientist, Base4 Inc., NC, USA

  • Dr. Allison Stelling

    • Postdoctoral Fellow 2015-2020
    • Presently Assistant Professor, Department of Chemistry, University of Texas at Dallas, TX, USA

  • Dr. Mary Clay

    • Postdoctoral Fellow 2014-2018
    • Presently Senior Research Technologist, Department of Structural Biology, St. Jude Children’s Research Hospital, TN, USA

  • Dr. Yi Xue

    • Postdoctoral Fellow 2014-2016
    • Presently Associate Professor, School of Life Sciences, Tsinghua University, Beijing, China
    • and Principal Investigator, Tsinghua-Peking Joint Center for Life Sciences, Beijing, China

  • Dr. Bharathwaj Sathyamoorthy

    • Postdoctoral Fellow 2013-2015
    • Presently Assistant Professor, Indian Institute of Science Education and Research, Bhopal, India

  • Dr. Loïc Salmon

    • Postdoctoral Fellow 2011-2014
    • Presently Assistant Professor, Claude Bernard University, Lyon, France
    • and CNRS Tenured Researcher, Very High Field NMR Center, Lyon, France

  • Dr. Jeetender Chugh

    • Postdoctoral Fellow 2010-2013
    • Presently Assistant Professor, Department of Chemistry, Indian Institute of Science Education and Research, Pune, India

  • Dr. Katja Petzold

    • Postdoctoral Fellow 2010-2013
    • Presently Principal Investigator, Dept. of Medical Biochemistry and Biophysics, Karolinska Institute, Solna, Sweden
    • and Professor, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden

Former Graduate Students

  • Dr. Akanksha Manghrani

    • Ph.D awarded in 2024, Biochemistry, Duke University
    • Presently Postdoctoral Researcher, IBBR Institute for Bioscience and Biotechnology Research, MD, USA

  • Dr. Stephanie Gu

    • Ph.D awarded in 2024, Biochemistry, Duke University
    • Presently Postdoctoral Fellow with Dr. Sua Myong, Boston Children’s Hospital, MA, USA

  • Dr. Megan L. Ken

    • Ph.D. awarded in 2022, Biochemistry (MSTP), Duke University
    • Presently Principal Investigator, Scripps Research, CA, USA

  • Dr. Atul Rangadurai

    • Ph.D. awarded in 2021, Biochemistry, Duke University
    • Presently Postdoctoral Fellow with Dr. Lewis E. Kay, University of Toronto, ON, Canada

  • Dr. Nicole Orlovsky

    • Ph.D. awarded in 2021, Biochemistry, Duke University
    • Presently Senior Expert, Novartis Institutes for BioMedical Research, MA, USA

  • Dr. Bei Liu

    • Ph.D. awarded in 2021, Biochemistry, Duke University
    • Presently Postdoctoral Fellow with Dr. Chuan He, University of Chicago, IL, USA

  • Dr. Honglue Shi

    • Ph.D. awarded in 2021, Chemistry, Duke University
    • Presently Postdoctoral Fellow with Dr. Jennifer Doudna, University of California Berkeley, CA, USA

  • Dr. Yu (Henry) Xu

    • Ph.D. awarded in 2021, Chemistry, Duke University
    • Presently Senior Consultant, ClearView Healthcare Partners, MA, USA

  • Dr. Chia-Chieh Chu

    • Ph.D. awarded in 2020, Biochemistry, Duke University
    • Presently Scientist, Tessera Therapeutics, MA, USA

  • Dr. Laura Ganser

    • Ph.D. awarded in 2019, Biochemistry, Duke University
    • Presently Postdoctoral Fellow with Dr. Sua Myong, John Hopkins University, MD, USA

  • Dr. Eric Szymanski

    • Ph.D. awarded in 2019, Biochemistry, Duke University
    • Presently Scientist, Base4 Inc., NC, USA

  • Dr. Dawn Merriman

    • Ph.D. awarded in 2018, Biochemistry, Duke University
    • Presently Associate Director of Clinical Evaluations, Alcon, MD, USA

  • Dr. Zachary Stein

    • Ph.D. awarded in in 2017, Biophysics, University of Michigan-Ann Arbor
    • Presently Data and Visualization Scientist, Booz Allen Hamilton, DC, USA

  • Dr. Huiqing (Jane) Zhou

    • Ph.D. awarded in 2016, Biochemistry, Duke University
    • Presently Assistant Professor, Department of Chemistry, Boston College, MA, USA

  • Dr. Anisha Shakya

    • Ph.D. awarded in 2016, Chemistry, University of Michigan-Ann Arbor
    • Presently Research Staff, Center for Soft and Living Matter, Institute of Basic Science, Ulsan, Korea

  • Dr. Issac Kimsey

    • Ph.D. awarded in 2016, Biochemistry, Duke University
    • Presently Vice President, Base4 Inc., NC, USA

  • Dr. Anthony Mustoe

    • Ph.D. awarded in 2014, Biophysics, University of Michigan-Ann Arbor
    • Presently Assistant Professor, Department of Biochemistry and Molecular Biology, Baylor College of Medicine, TX, USA

  • Dr. Heidi Alvey

    • Ph.D. awarded in 2014, Chemistry, University of Michigan-Ann Arbor

  • Dr. Janghyun (Kevin) Lee

    • Ph.D. awarded in 2014, Chemistry, University of Michigan-Ann Arbor
    • Presently Director, InterVest Co., LTD, Seoul, Korea

  • Dr. Shan Yang

    • Ph.D. awarded in 2014, Chemistry, University of Michigan-Ann Arbor
    • Presently Associate Director, Novartis, Jiangsu, China

  • Dr. Joseph Yesselman

    • Ph.D. awarded in 2014, Biophysics, University of Michigan-Ann Arbor
    • Presently Assistant Professor, Department of Chemistry, University of Nebraska-Lincoln, NE, USA

  • Dr. Scott Horowitz

    • Ph.D. awarded in 2013, Biophysics, University of Michigan-Ann Arbor
    • Presently Assistant Professor, Department of Chemistry and Biochemistry, University of Denver, CO, USA

  • Dr. Jameson Bothe

    • Ph.D. awarded in 2012, Chemistry, University of Michigan-Ann Arbor
    • Presently Principal Scientist, Merck Research Laboratories, NJ, USA

  • Dr. Catherine Eichhorn

    • Ph.D. awarded in 2012, Chemistry, University of Michigan-Ann Arbor
    • Presently Assistant Professor, Department of Chemistry, University of Nebraska-Lincoln, NE, USA

  • Dr. Liz Dethoff

    • Ph.D. awarded in 2011, Chemistry, University of Michigan-Ann Arbor
    • Presently Scientist, Ribometrix Inc., NC, USA

  • Dr. Evgenia Nikolova

    • Ph.D. awarded in 2011, Chemical Biology, University of Michigan-Ann Arbor
    • Presently Assistant Research Professor, Department of Biophysics, Johns Hopkins University, MD, USA

  • Dr. Anette Casiano-Negroni

    • Ph.D. awarded in 2010, Chemistry, University of Michigan-Ann Arbor
    • Presently Assistant Professor, Department of Chemistry, Trinity Washington University, DC, USA

  • Dr. Maximillian Bailor

    • Ph.D. awarded in 2010, Chemistry, University of Michigan-Ann Arbor
    • Presently Senior Medical Director, Symbiotix LLC, NY, USA

  • Dr. Andrew Stelzer

    • Ph.D. awarded in 2010, Biophysics, University of Michigan-Ann Arbor
    • Presently Head of Business Development, Unlearn.AI, CA, USA

  • Dr. Alexandar L. Hansen

    • Ph.D. awarded in 2009, Chemistry, University of Michigan-Ann Arbor
    • Presently Principal Investigator and Research Scientist, CCIC NMR Facility, Ohio State University, OH, USA

  • Dr. Xiaoyan (Jennifer) Sun

    • Ph.D. awarded in 2008, Chemistry, University of Michigan-Ann Arbor
    • Presently Adjunct Research Assistant Professor, Department of Chemistry, North Carolina State University, NC, USA

  • Dr. Catherine Musselman

    • Ph.D. awarded in 2007, Chemistry, University of Michigan-Ann Arbor
    • Presently Associate Professor, Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz, CO, USA

  • Dr. Melissa Getz

    • Ph.D. awarded in 2007, Chemistry, University of Michigan-Ann Arbor

  • Dr. Qi Zhang

    • Ph.D. awarded in 2007, Chemistry, University of Michigan-Ann Arbor
    • Presently Associate Professor, Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, NC, USA

Former Master's and Undergraduate Students

  • John Boom

    • 2020-2022, Duke University
    • Presently M.Phil. Student in Machine Learning, University of Cambridge, Cambridge, UK

  • Amy Liu

    • 2018-2021, Duke University

  • Cassie Yuan

    • 2015-2017, Duke University
    • Presently Ph.D. Student in Pharmacology, Weill Cornell Medicine, NY, USA

  • Tim Bai

    • 2014-2016, Duke University
    • Presently M.D. Student, New York Medical College, NY, USA

  • Jeremy Kratz

    • 2007-2011, University of Michigan-Ann Arbor
    • Presently Assistant Professor, Department of Medicine, University of Wisconsin-Madison, WI, USA

  • Charles Fisher

    • 2006-2008, University of Michigan-Ann Arbor
    • Presently Founder and CEO, Unlearn.AI, CA, USA

  • Rachel Throolin

    • M.S. awarded in 2004, Chemistry, University of Michigan-Ann Arbor